Ongoing symptoms like digestive issues, skin problems, or chronic sinus congestion often leads  people to suspect allergies. But figuring out the exact triggers can be tricky without the right  kind of testing. Two frequently used methods are IgG (Immunoglobulin G) and IgE  (Immunoglobulin E) tests. While both relate to immune responses, they serve very different  purposes. Understanding how these tests work and what they reveal can help you make more  informed decisions about your allergy management and overall health strategy. 

What is IgG and IgE Antibodies? 

Antibodies are proteins made by the immune system to identify and fight off harmful  substances like viruses, bacteria and allergens. Each type targets specific invaders to help keep  the body healthy. The immune system relies on different types of antibodies to defend the body,  with IgE and IgG playing distinct roles in immune responses.  

IgE antibodies are responsible for immediate allergic reactions, which happen within minutes of  exposure to an allergen—like sneezing around pollen or developing hives after eating peanuts. 

In contrast, IgG antibodies are linked to delayed responses that can occur hours or even days  later. These reactions are typically associated with food sensitivities rather than classic allergic  reactions. 

IgE Testing: For Immediate Allergic Reactions 

IgE (Immunoglobulin E) testing is used to identify immediate allergic responses that occur  within minutes of exposure to allergens like pollen, pet dander, or certain foods. These reactions  can include symptoms such as hives, itching, swelling, sneezing, or even anaphylaxis. IgE tests  help pinpoint specific allergens, guiding treatment plans such as avoidance strategies or allergy  shots. 

When to consider an IgE test: 

If you develop symptoms such as rashes, itching, swelling, asthma, or anaphylaxis soon after  eating or coming into contact with a substance, an IgE test may be helpful. It can identify  specific allergens and support treatment plans, including avoidance, antihistamines, or allergy  shots. 

IgG Testing: For Delayed Food Sensitivities 

IgG (Immunoglobulin G) testing is used to detect delayed food sensitivities that may cause  symptoms hours or even days after consumption. Unlike immediate allergic reactions, IgG  responses are linked to non-life-threatening conditions like digestive discomfort, bloating, brain, 

fatigue fog or headaches. This test helps identify foods that may be contributing to these  delayed reactions, allowing for dietary adjustments to improve overall well-being. 

Unlike IgE reactions, IgG responses are generally not life-threatening but can still affect your  quality of life. While these tests are somewhat controversial in the medical field, as their  diagnostic accuracy is debated, many integrative and functional medicine practitioners use IgG  tests to support elimination diets and identify possible food triggers. 

When to consider an IgG test: 

If you experience unexplained, chronic symptoms without a clear allergen, IgG testing may help  pinpoint food sensitivities that could be causing systemic inflammation or discomfort. 

Here’s a comparative table to highlight the differences between IgE and IgG:

Which Test is Right for You? 

The choice between IgE and IgG testing depends on your symptoms and health objectives: Symptom Type Recommended Test 

• Immediate reactions (e.g., swelling, hives, anaphylaxis) IgE Test 
• Delayed symptoms (e.g., bloating, fatigue, skin issues) IgG Test
• Chronic, non-specific symptoms - consider both tests 

A healthcare provider or allergist can help you interpret your results and suggest the best  treatment approach, whether through avoidance, dietary adjustments, or medical care. 

How is IgE & IgG Test done? 

During both tests, a healthcare provider will take a blood sample from a vein in your arm. The  sample is analyzed in a laboratory & the levels of IgE and IgG antibodies are measured. The IgE test measures antibodies related to allergic responses, often indicating sensitivity to allergens  like pollen, food, or pet dander. On the other hand, the IgG test measures antibodies linked to  immune responses to infections or chronic sensitivities, including food intolerances (though its  

use for food sensitivities is debated).  

Elevated IgE levels can indicate an allergy, while high IgG levels can suggest previous infections  or long-term exposure to certain substances. Both tests are valuable in understanding your  immune system's reactions, but results are interpreted alongside your clinical symptoms and  history. These tests provide important information, but the results are best considered as part  of a broader assessment by a healthcare professional. 

IgE & IgG Testing at Medivision 

Medivision offers IgE and IgG blood tests to help detect allergies, immune responses and  possible food sensitivities. With a quick and simple blood draw, our advanced lab technology  delivers accurate results to support personalized treatment plans. Fast, accurate and handled by  experts—your health, decoded. Whether you're dealing with unexplained symptoms or 

managing known allergies, Medivision ensures reliable testing and expert care every step of the  way. 

Final Thoughts 

Understanding the difference between IgG and IgE testing can help you make smarter, more  informed choices about your allergy care. IgE tests are designed to detect immediate and  potentially serious allergic reactions, while IgG tests provide insights into delayed food  sensitivities that may affect your long-term health. Selecting the right test—or combining  both—can lead to more personalized, accurate and effective allergy management.